R. Wesker got injected by the prototype/experimental Virus.
There are no radical visible physical changes exhibited by a fully adapted subject. The only visible change in adaptable subjects is the shape and color of their eyes, which become slitted orange-yellow, and glow red when expressing emotions such as anger and rage, or when exerting energy. If adapted perfectly, the virus completely recombines the host's cells, strengthening the body and enhancing muscle power and neural reflexes, granting super strength, speed, agility and other biological and genetic improvements such as an enhanced metabolism and higher-density mitochondria. The virus exhibits an astounding regeneration capability, and virtually no conventional weapon can damage the host; however, the virus presents no defense against fire although burns, like all other wounds, heal quickly with no tissue scarring.
In other cases, the virus simply revives the subject with no physical or biological changes thereafter.